RO
RU
EN
Clasament
| Loc | Echipă | Meci | Victorii | Egalități | Înfrângeri | Golaveraj | Puncte |
| 1. | FC Regal | 20 | 18 | 1 | 1 | 74-12 | 55 |
| 2. | Dacia-Buiucani 2 | 20 | 16 | 2 | 2 | 91-37 | 50 |
| 3. | Milsami-CFSS Orhei | 20 | 16 | 1 | 3 | 125-17 | 49 |
| 4. | CS Getica | 20 | 13 | 1 | 6 | 66-33 | 40 |
| 5. | CSF Măgdăcești | 20 | 10 | 0 | 10 | 45-55 | 30 |
| 6. | FC Cahul 2005 | 20 | 7 | 3 | 10 | 24-38 | 24 |
| 7. | Zimbru 2 | 20 | 7 | 3 | 10 | 38-55 | 24 |
| 8. | FC Olimpic | 20 | 5 | 2 | 13 | 26-55 | 17 |
| 9. | Sheriff 2 | 20 | 5 | 1 | 14 | 34-80 | 16 |
| 10. | CS Fulger | 20 | 3 | 0 | 17 | 17-75 | 9 |
| 11. | SMART | 20 | 3 | 0 | 17 | 29-112 | 9 |
| Nr | Data | Echipele | Scor | Terenul | Ora | |
Etapa I | ||||||
| 1 | Dacia-Buiucani 2 - liberă | |||||
| 2 | 11.09.2021 | Zimbru 2 - CS Getica | 2-5 | Zimbru | 12:00 | |
| 3 | 13.10.2021 | CS Fulger - SMART | 5-2 | Ialoveni | 16:00 | |
| 4 | 12.09.2021 | Milsami-CFSS Orhei - CSF Măgdăcești | 9-0 | CSR Orhei | 12:00 | |
| 5 | 11.09.2021 | FC Regal - Sheriff 2 | 6-0 | CS Sheriff | 11:00 | |
| 6 | 11.09.2021 | FC Cahul 2005 - FC Olimpic | 0-1 | Cahul | 14:30 | |
Etapa II | ||||||
| 7 | 19.09.2021 | Dacia-Buiucani 2 - FC Olimpic | 8-2 | Joma Arena | 10:30 | |
| 8 | 18.09.2021 | Sheriff 2 - FC Cahul 2005 | 1-1 | Sheriff | 12:00 | |
| 9 | 18.09.2021 | CSF Măgdăcești - FC Regal | 2-3 | Ratuș | 15:00 | |
| 10 | 18.09.2021 | SMART - Milsami-CFSS Orhei | 0-9 | Mileștii Mici | 11:30 | |
| 11 | 19.09.2021 | CS Getica - CS Fulger | 10-0 | Zimbru | 10:30 | |
| 12 | 19.09.2021 | Zimbru 2 - liberă | ||||
Etapa III | ||||||
| 13 | 25.09.2021 | Zimbru 2 - Dacia-Buiucani 2 | 4-4 | Zimbru | 10:00 | |
| 14 | 26.09.2021 | Milsami-CFSS Orhei - CS Getica | 5-0 | CSR Orhei | 12:30 | |
| 15 | 23.09.2021 | FC Regal - SMART | 8-2 | c.sp. Ghidighici | 17:00 | |
| 16 | 25.09.2021 | FC Cahul 2005 - CSF Măgdăcești | 5-0 | Cahul | 12:00 | |
| 17 | 26.09.2021 | FC Olimpic - Sheriff 2 | 1-2 | S.Galbenă | 13:00 | |
| 18 | CS Fulger - liberă | |||||
Etapa IV | ||||||
| 19 | 02.10.2021 | Dacia-Buiucani 2 - Sheriff 2 | 8-2 | Joma Arena | 11:00 | |
| 20 | 02.10.2021 | CSF Măgdăcești - FC Olimpic | 3-0 | Ratuș | 09:00 | |
| 21 | 03.10.2021 | SMART - FC Cahul 2005 | 0-2 | Mileștii Mici | 13:30 | |
| 22 | 02.10.2021 | CS Getica - FC Regal | 0-1 | Zimbru | 10:00 | |
| 23 | 02.10.2021 | Zimbru 2 - CS Fulger | 1-0 | Zimbru | 09:00 | |
| 24 | Milsami-CFSS Orhei - liberă | |||||
Etapa V | ||||||
| 25 | 09.10.2021 | CS Fulger - Dacia-Buiucani 2 | 3-10 | Ialoveni | 11:00 | |
| 26 | 09.10.2021 | Milsami-CFSS Orhei - Zimbru 2 | 7-0 | CSR Orhei | 11:30 | |
| 27 | FC Regal - liberă | c.sp. Ghidighici | ||||
| 28 | 10.10.2021 | FC Cahul 2005 - CS Getica | 1-2 | Cahul | 12:00 | |
| 29 | 09.10.2021 | FC Olimpic - SMART | 2-5 | S.Galbenă | 11:00 | |
| 30 | 10.10.2021 | Sheriff 2 - CSF Măgdăcești | 5-1 | Sheriff | 12:00 | |
Etapa VI | ||||||
| 31 | 16.10.2021 | Dacia-Buiucani 2 - CSF Măgdăcești | 3-1 | Joma Arena | 11:00 | |
| 32 | 17.10.2021 | SMART -Sheriff 2 | 1-0 | Mileștii Mici | 13:30 | |
| 33 | 14.10.2021 | CS Getica - FC Olimpic | 3-1 | Zimbru | 15:00 | |
| 34 | 13.10.2021 | Zimbru 2 - FC Regal | 0-2 | Zimbru | 18:00 | |
| 35 | 17.10.2021 | CS Fulger - Milsami-CFSS Orhei | 0-8 | Ialoveni | 12:30 | |
| 36 | FC Cahul 2005 - liberă | |||||
Etapa VII | ||||||
| 37 | 24.10.2021 | Milsami-CFSS Orhei - Dacia-Buiucani 2 | 4-0 | CSR Orhei | 12:30 | |
| 38 | 26.10.2021 | FC Regal - CS Fulger | 4-0 | c.sp. Ghidighici | 11:00 | |
| 39 | 24.10.2021 | FC Cahul 2005 - Zimbru 2 | 1-1 | Cahul | 11:30 | |
| 40 | 23.10.2021 | Sheriff 2 - CS Getica | 1-2 | Sheriff | 12:00 | |
| 41 | 23.10.2021 | CSF Măgdăcești - SMART | 4-1 | Ratuș | 11:30 | |
| 42 | FC Olimpic - liberă | |||||
Etapa VIII | ||||||
| 43 | 28.10.2021 | Dacia-Buiucani 2 - SMART | 5-4 | Joma Arena | 11:30 | |
| 44 | 28.10.2021 | CS Getica - CSF Măgdăcești | 5-1 | Zimbru | 11:30 | |
| 45 | 28.10.2021 | Zimbru 2 - FC Olimpic | 0-1 | Zimbru | 10:00 | |
| 46 | 30.10.2021 | CS Fulger - FC Cahul 2005 | 0-1 | Ialoveni | 12:00 | |
| 47 | 30.10.2021 | Milsami-CFSS Orhei - FC Regal | 0-1 | CSR Orhei | 11:30 | |
| 48 | Sheriff 2 - liberă | |||||
Etapa IX | ||||||
| 49 | 28.11.2021 | FC Regal - Dacia-Buiucani 2 | 3-0 | Joma Arena | 12:30 | |
| 50 | 07.11.2021 | FC Cahul 2005 - Milsami-CFSS Orhei | 0-3 | Cahul | 12:30 | |
| 51 | 06.11.2021 | FC Olimpic - CS Fulger | 0-1 | S.Galbenă | 12:30 | |
| 52 | 06.11.2021 | Sheriff 2 - Zimbru 2 | 2-6 | Sheriff | 12:30 | |
| 53 | 04.11.2021 | SMART - CS Getica | 1-8 | Ialoveni | 15:00 | |
| 54 | CSF Măgdăcești - liberă | |||||
Etapa X | ||||||
| 55 | 13.11.2021 | Dacia-Buiucani 2 - CS Getica | 1-1 | Joma Arena | 10:30 | |
| 56 | 13.11.2021 | Zimbru 2 - CSF Măgdăcești | 4-0 | Zimbru | 11:30 | |
| 57 | 13.11.2021 | CS Fulger - Sheriff 2 | 6-1 | Ialoveni | 12:30 | |
| 58 | 13.11.2021 | Milsami-CFSS Orhei - FC Olimpic | 9-0 | CSR Orhei | 10:30 | |
| 59 | 14.11.2021 | FC Regal - FC Cahul 2005 | 5-0 | c.sp. Ghidighici | 13:30 | |
| 60 | SMART - liberă | |||||
Etapa XI | ||||||
| 61 | 21.11.2021 | FC Cahul 2005 - Dacia-Buiucani 2 | 0-2 | Cahul | 11:00 | |
| 62 | 20.11.2021 | FC Olimpic - FC Regal | 0-2 | Stăuceni | 12:30 | |
| 63 | 21.11.2021 | Sheriff 2 - Milsami-CFSS Orhei | 0-14 | Sheriff | 13:00 | |
| 64 | 20.11.2021 | CSF Măgdăcești - CS Fulger | 4-0 | Ratuș | 12:30 | |
| 65 | 21.11.2021 | SMART - Zimbru 2 | 2-6 | Ialoveni | 12:30 | |
| 66 | CS Getica - liberă | Zimbru | ||||
Etapa XII | ||||||
| 67 | 26.03.2022 | CS Getica - Zimbru 2 | 2-0 | Chișinău, LT N. Iorga | 10:00 | |
| 68 | 26.03.2022 | SMART - CS Fulger | 3-0 | Ialoveni | 11:30 | |
| 69 | 26.03.2022 | CSF Măgdăcești - Milsami-CFSS Orhei | 0-7 | Ratuș | 11:30 | |
| 70 | 26.03.2022 | Sheriff 2 - FC Regal | 0-5 | Sheriff | 11:30 | |
| 71 | 26.03.2022 | FC Olimpic - FC Cahul 2005 | 2-1 | S.Galbenă | 13:30 | |
| 72 | Dacia-Buiucani 2 - liberă | |||||
Etapa XIII | ||||||
| 73 | 03.04.2022 | FC Olimpic - Dacia-Buiucani 2 | 2-6 | S.Galbenă | 10:30 | |
| 74 | 02.04.2022 | FC Cahul 2005 - Sheriff 2 | 3-2 | Cahul | 14:00 | |
| 75 | 01.04.2022 | FC Regal - CSF Măgdăcești | 4-2 | Stăuceni sint. | 15:00 | |
| 76 | 03.04.2022 | Milsami-CFSS Orhei - SMART | 17-0 | CSR Orhei | 11:30 | |
| 77 | 02.04.2022 | CS Fulger - CS Getica | 1-6 | Ialoveni | 11:30 | |
| 78 | Zimbru 2 - liberă | Zimbru | ||||
Etapa XIV | ||||||
| 79 | 09.04.2022 | Dacia-Buiucani 2 - Zimbru 2 | 4-1 | Joma Arena | 10:30 | |
| 80 | CS Fulger - liberă | |||||
| 81 | 10.04.2022 | CS Getica - Milsami-CFSS Orhei | 1-4 | LT N. Iorga | 12:30 | |
| 82 | 10.04.2022 | SMART - FC Regal | 1-10 | Ialoveni | 11:30 | |
| 83 | 10.04.2022 | CSF Măgdăcești - FC Cahul 2005 | 4-1 | Drăsliceni | 14:00 | |
| 84 | 10.04.2022 | Sheriff 2 - FC Olimpic | 2-1 | Sheriff | 11:00 | |
Etapa XV | ||||||
| 85 | 16.04.2022 | Sheriff 2 - Dacia-Buiucani 2 | 0-5 | Sheriff | 10:00 | |
| 86 | 17.04.2022 | FC Olimpic - CSF Măgdăcești | 1-3 | Drăsliceni | 12:00 | |
| 87 | 17.04.2022 | FC Cahul 2005 - SMART | 3-0 | Cahul | 12:30 | |
| 88 | 17.04.2022 | FC Regal - CS Getica | 3-0 | LT N. Iorga | 10:00 | |
| 89 | 17.04.2022 | CS Fulger - Zimbru 2 | 0-4 | Ialoveni | 11:30 | |
| 90 | Milsami-CFSS Orhei - liberă | |||||
Etapa XVI | ||||||
| 91 | Dacia-Buiucani 2 - CS Fulger | 3-0 | Joma Arena | |||
| 92 | 23.04.2022 | Zimbru 2 - Milsami-CFSS Orhei | 0-11 | Zimbru | 12:30 | |
| 93 | FC Regal - liberă | Dinamo | ||||
| 94 | 23.04.2022 | CS Getica - FC Cahul 2005 | 3-0 | LT N. Iorga | 13:00 | |
| 95 | 23.04.2022 | SMART - FC Olimpic | 1-2 | Ialoveni | 12:30 | |
| 96 | 23.04.2022 | CSF Măgdăcești - Sheriff 2 | 1-0 | Stăuceni sint. | 12:00 | |
Etapa XVII | ||||||
| 97 | 28.04.2022 | CSF Măgdăcești - Dacia-Buiucani 2 | 1-4 | Drăsliceni | 11:30 | |
| 98 | 11.05.2022 | Sheriff 2 - SMART | 8-4 | Sheriff | 16:00 | |
| 99 | 28.04.2022 | FC Olimpic - CS Getica | 2-3 | LT N. Iorga | 12:00 | |
| 100 | FC Cahul 2005 - liberă | Cahul | ||||
| 101 | 30.04.2022 | FC Regal - Zimbru 2 | 8-0 | LT N. Iorga | 11:00 | |
| 102 | Milsami-CFSS Orhei - CS Fulger | 3-0 | Drăsliceni | |||
Etapa XVIII | ||||||
| 103 | 07.05.2022 | Dacia-Buiucani 2 - Milsami-CFSS Orhei | 8-3 | Joma Arena | 14:00 | |
| 104 | CS Fulger - FC Regal | 0-3 | Ialoveni | |||
| 105 | 07.05.2022 | Zimbru 2 - FC Cahul 2005 | 0-2 | Zimbru | 13:00 | |
| 106 | FC Olimpic - liberă | Dinamo | ||||
| 107 | 07.05.2022 | CS Getica - Sheriff 2 | 8-2 | LT N. Iorga | 13:30 | |
| 108 | 05.05.2022 | SMART - CSF Măgdăcești | 0-9 | Ialoveni | 18:00 | |
Etapa XIX | ||||||
| 109 | 15.05.2022 | SMART - Dacia-Buiucani 2 | 2-7 | Ialoveni | 12:30 | |
| 110 | 11.05.2022 | CSF Măgdăcești - CS Getica | 5-3 | Ratuș | 17:00 | |
| 111 | Sheriff 2 - liberă | Sheriff | ||||
| 112 | 14.05.2022 | FC Olimpic - Zimbru 2 | 2-2 | Zimbru | 10:00 | |
| 113 | FC Cahul 2005 - CS Fulger | 3-0 | Cahul | |||
| 114 | 14.05.2022 | FC Regal - Milsami-CFSS Orhei | 2-0 | LT N. Iorga | 11:00 | |
Etapa XX | ||||||
| 115 | 18.05.2022 | Dacia-Buiucani 2 - FC Regal | 4-2 | Joma Arena | 15:30 | |
| 116 | 21.05.2022 | Milsami-CFSS Orhei - FC Cahul 2005 | 6-0 | Ratuș | 13:00 | |
| 117 | CS Fulger - FC Olimpic | 0-3 | Ialoveni | |||
| 118 | 22.05.2022 | Zimbru 2 - Sheriff 2 | 3-1 | Zimbru | 13:00 | |
| 119 | CSF Măgdăcești - liberă | Dinamo | ||||
| 120 | 21.05.2022 | CS Getica - SMART | 3-0 | LT N. Iorga | 12:00 | |
Etapa XXI | ||||||
| 121 | 28.05.2022 | CS Getica - Dacia-Buiucani 2 | 1-3 | LT N. Iorga | 11:30 | |
| 122 | SMART - liberă | Ialoveni | ||||
| 123 | 25.05.2022 | CSF Măgdăcești - Zimbru 2 | 1-0 | Ratuș | 16:00 | |
| 124 | Sheriff 2 - CS Fulger | 3-0 | Sheriff | |||
| 125 | 28.05.2022 | FC Olimpic - Milsami-CFSS Orhei | 2-2 | S.Galbenă | 11:30 | |
| 126 | 28.05.2022 | FC Cahul 2005 - FC Regal | 0-0 | Cahul | 12:00 | |
Etapa XXII | ||||||
| 127 | 02.06.2022 | Dacia-Buiucani 2 - FC Cahul 2005 | 6-1 | Joma Arena | 14:30 | |
| 128 | 25.05.2022 | FC Regal - FC Olimpic | 2-1 | LT N. Iorga | 18:00 | |
| 129 | 02.06.2022 | Milsami-CFSS Orhei - Sheriff 2 | 4-2 | Drăsliceni | 14:30 | |
| 130 | CS Fulger - CSF Măgdăcești | 0-3 | Ialoveni | |||
| 131 | 02.06.2022 | Zimbru 2 - SMART | 4-0 | Zimbru | 14:30 | |
| 132 | CS Getica - liberă | |||||